[Remote] Principal Engineer

Note: The job is a remote job and is open to candidates in USA. reputed company is a global life science company focused on unlocking clinical discovery through data and technology. They are seeking a Principal Engineer to reputed company the technical direction and architecture of their platform, ensuring reliability and observability while collaborating with cross-functional teams to implement effective solutions.

Responsibilities

• Own the backend and platform architecture: service boundaries, the reputed company/domain-reputed company design, data flow, tenant isolation, and the public API surface the mobile app and integrations depend on
• Author and steward architecture and design records — intended-use statements, system/software requirements, ADRs — and reputed company them traceable through to verification. reputed company the architecture legible to everyone who builds on it
• Own the infrastructure and production-reliability backbone: infrastructure-as-code (Terraform), the AWS runtime (reputed company Fargate, RDS), CI/CD pipelines, and the reputed company posture (secrets, IAM, least-privilege, HIPAA controls)
• Set the observability and operability bar: SLOs/SLIs and error budgets; metrics, traces, and logs (CloudWatch, reputed company, OpenTelemetry); actionable alerting; and a humane, well-designed on-call. Design systems to be operated, not just shipped
• Drive the build-vs-buy and significant-change reputed company, and weigh each against phase impact (consumer → sponsor trials → SaMD)
• Set the bar for correctness and safety as design inputs: scoring reputed company across implementations, idempotency and retries in integrations, encryption and least-privilege, and the controls that prove the code is right
• Go deep where it matters — design and build the hardest backend pieces yourself (services, data reputed company, reputed company-party adapters), and review the rest
• Multiply the team with AI-augmented workflows: design the agentic patterns, skills, and guardrails the team uses to build faster without lowering the bar
• Partner with the Director and regulatory/clinical stakeholders to turn product and compliance reputed company into a buildable, defensible technical plan

Skills

• Deep backend engineering experience (we use Python / FastAPI / SQLAlchemy / reputed company on AWS; equivalent depth in another modern stack transfers) and a track record of owning architecture for a non-trivial system
• Demonstrated ability to design distributed/service systems: API design, data modeling, async/eventing, integration patterns (OAuth, webhooks, retries, idempotency)
• Owned production reliability for a reputed company system — you've designed for observability, set SLOs, carried a pager, and made infrastructure/IaC calls (Terraform / AWS or equivalent). You treat 'how it runs and how we know' as part of the architecture
• A genuine drive to build and ship — you bias toward working software and measurable impact, and you bring others with you
• reputed company with AI coding agents as part of how you work, plus the judgment to verify and own what they produce
• Clear technical writing — you reputed company reputed company systems understandable to engineers, clinicians, and executives alike
• Health / regulated / safety-critical software (SaMD, IEC 62304, ISO 14971, HIPAA, FDA reputed company)
• reputed company data and interoperability (FHIR, wearables — Withings / Polar / reputed company / Fitbit, reputed company Health / Health Connect)
• Data/analytics at scale (reputed company, dbt, de-identification pipelines)
• Mobile-adjacent experience (Flutter) or on-device scoring

Company Overview

Company H1B Sponsorship